Algoritmo para la indicación del estudio por imágenes en pacientes politraumatizados

Introducción: En los últimos años se han producido cambios profundos en el manejo del paciente politraumatizado. A la vez, se han desarrollado nuevos conceptos en relación con las posibles complicaciones, los esquemas de tratamiento y las escalas pronósticas, así como en la identificación de elementos relacionados con su evolución para determinar, de manera precoz, las lesiones que amenazan la vida y precisan de un control quirúrgico inmediato o de intervencionismo radiológico. La tomografía computarizada multicorte y otros estudios imagenológicos permiten la obtención de imágenes de las estructuras corporales por planos, y proporcionan información muy detallada y útil para el diagnóstico; sin embargo, no existe consenso a la hora de indicar uno u otro en el trauma. Objetivo: Elaborar un algoritmo para la indicación eficiente de los estudios imagenológicos en el paciente politraumatizado. Materiales y métodos: Se ejecutó una investigación de desarrollo tecnológico, donde el universo de trabajo estuvo conformado por 43 pacientes con criterio de politrauma -que necesitaron estudios imagenológicos-, ingresados en el Hospital Universitario Clínico Quirúrgico Comandante Faustino Pérez Hernández, en el período comprendido entre marzo de 2020 y marzo de 2021. Resultados: Se elaboró un algoritmo para estandarizar la indicación de estudios imagenológicos en el trauma. Este trabajo considera la seguridad y protección del paciente, y el cuidado de la vida útil del equipo de tomografía axial computarizada. Conclusión: El algoritmo diseñado viabiliza la toma de decisiones respecto al uso de recursos imagenológicos en la atención a los pacientes politraumatizados.

Introduction: In recent years there have been profound changes in the management of poly-traumatized patients. At the same time, new concepts have been developed in relation to possible complications, treatment schemes and prognostic scales, as well as in the identification of elements related with its evolution to early determine the life-threatening lesions and require immediate surgical control or radiological intervention. Multislice computed tomography and other imaging studies allow obtaining images of body structures by planes and provide very detailed and useful information for the diagnosis; nevertheless there is no consensus when it comes to indicating one or the other in trauma. Objective: To develop an algorithm for the efficient indication of imaging study in the poly-traumatized patient. Materials and methods: A technological development research was carried out, where the working universe was made up by 43 patients with polytrauma criteria -who needed imaging studies- admitted to the Clinical Surgical University Hospital Faustino Perez, in the period between March 2020 and March 2021. Results: An algorithm was developed for standardizing the indication of imaging studies in trauma. This work considers the safety and protection of the patient, and the care of the life of the computed axial tomography equipment. Conclusions: The developed algorithm enables decision-making regarding the use of imaging resources in the care of poly-traumatized patients.

Retrospective study on the types and characteristics of shock in polytrauma patients at different stages after trauma / 中华急诊医学杂志

Objective:To investigate the types, incidences, and clinical characteristics of shock in polytrauma patients at different stages after polytrauma.Methods:A retrospective study was conducted on polytrauma patients admitted to multiple trauma centers from June 2020 to December 2021. The inclusion criteria were patients >18 years old and treated due to polytrauma. Exclusion criteria included an admission time of more than 48 h after trauma, a history of malignancy, or metabolic, consumptive, and immunological diseases. The early stage was defined as the period of ≤48 h after polytrauma, and the middle stage was defined as the period between 48 h and 14 days. The patient’s medical history, clinical manifestations, laboratory tests, imaging examination, injury severity score (ISS), and Glasgow coma scale (GCS) were collected. The types, incidences, and clinical characteristics of shock in different stages after polytrauma were analyzed, according to the diagnostic criteria of each type of shock. The differences between the groups were compared by Student’s t test, χ2 test or Mann-Whitney U test. Results:The incidence of the early and middle stage shock after polytrauma were 73.1% and 36.4%, respectively, with statistically significant difference between stages ( P<0.01). There were significant differences in the incidence of hypovolemic shock (83.6% vs. 28.4%), distributed shock (13.7% vs. 80.9%) and cardiogenic shock (3.5% vs. 6.6%) between stages (all P<0.05). The incidence of obstructive shock (8.4% vs. 9.7%, P>0.05) was similar between stages. The incidence of undifferentiated shock was 1.6% and 1.2%, respectively. There were 9.5% patients with multifactorial shock in the early stage and 14.4% in the middle stage. Totally 7 combinations of multifactorial shock were found in different stages after polytrauma. In the early stage, the combination of HS and DS accounted the highest ratio (42.3%) and followed by HS and OS for 28.8%. In the middle stage, the combination of HS and DS was the most common (48.6%) and followed by DS and OS (24.3%). Conclusions:The incidence of shock in polytrauma patients is high. Different types of shock can occur simultaneously or sequentially. Therefore a comprehensive resuscitation strategy is significant to improve the success rate of treatment.

Evaluate the incidence, topography, management, and outcomes in patients with polytrauma in the Suez Canal and Sinai areas

Introduction: The global prevalence of trauma-related mortality ranges from 2% to 32%; however, In Egypt, it reaches 8%. Trauma chiefly affects people in the productive age group; seriously ill patients with multiple injuries present with various levels of polytrauma. Application of incorrect triage systems and improperly trained trauma teams increase mortality and morbidity rates in non-dedicated institutions; however, these rates can decrease with appropriate infrastructure. This study aimed to improve the quality of care for patients with polytrauma through improved knowledge of the different severity levels of polytrauma and defined databases, using a suitable triage trauma system, well-trained trauma team, and appropriate infrastructure. Methods: This observational cross-sectional study was conducted at the emergency department (ED), over a study period of 7 months, from August 10, 2019, to March 09, 2020. This study included 458 patients with polytrauma who had met the inclusion and exclusion criteria and attended the ED of Suez Canal University Hospital. Results: The incidence of trauma among all emergency cases in the ED was 5.3%. However, most multiple injuries are mild, accounting for 44.4%, while 27.3% of the cases had life-threatening injuries. Moreover, 41.9% of the patients were managed non-operatively, whereas 58.1% of the patients required surgical interventions. Concerning the outcome, 56% and 6.9% of patients with and without life-threatening injuries respectively, died. Conclusion: Facilities of the highest quality should be available for patients with polytrauma, especially those with life-threatening injuries. In addition, training emergency medical service staff for trauma triage is essential, and at least one tertiary hospital is required in every major city in the Suez Canal and Sinai areas to decrease trauma-related mortality.

Comparative Study of Outcome of Treatment of Fracture Shaft of Femur by Open Intramedullary Kuntscher抯 Nail and Closed Intramedullary Interlocking Nail

Fractures of the femoral shaft are one of the most common injuries treated by orthopedic surgeons. These fractures are often associated with polytrauma and can be life-threatening.For physiologically stable individuals, Intramedullary Nailing (IMN) is the most prevalent therapy. Early healing and long-term functional recovery are the goals of fixation. Treatment of modern-day femoral shaft fractures results in excellent outcomes. Aims : To assess the results of intramedullary nailing of femoral shaft fractures by both open and closed methods. Methods : Primary, non-randomized, prospective cohort study, Patients having fracture shaft of femur who was admitted in MGM Medical College & LSK Hospital, Kishanganj was taken for the study, The study period from October 2019 to April 2021. Total 40 cases were enrolled, Open Kuntcher抯 Nail-20 cases & Closed Interlocking Nail-20 cases. Results : Male cases are predominantly high than females among the two groups. Maximum number of fracture (70% in Closed Interlocking Nail group and 80% in Open K-nail group) Radiological union within 15 weeks.Maximum number of the cases found excellent results in both groups. ie, 70% & 65% respectively. In this study, we have not found any poor & fair patients after surgical outcome. Chi-square value 0.1139 & P-value- is 0.735. Conclusion : Except for the period from injury to surgery and operating time, there was no significant difference between the two groups in terms of demographic data, fracture type, and associated co-morbidities and radiological union. When utilised to fix short oblique and transverse fractures near the isthmus of the femur, Kuntscher抯 intramedullary nailing can yield a comparable rate of union to interlocking intramedullary nailing.

Early risk factors for persistent inflammation immunosuppression and catabolism syndrome in patients with severe polytrauma / 中华急诊医学杂志

Objective:To retrospectively assess early risk factor of persistent inflammation, immunosuppression and catabolism syndrome (PICS) in patients with severe polytrauma, in order to deepen the understanding of the pathological changes of chronic critical illness (CCI) after severe polytrauma.Methods:A total of 276 patients with severe polytrauma admitted to Department of Trauma Surgery of Tongji Hospital from March 2019 to December 2020 were enrolled. Inclusion criteria included patients who suffered severe polytrauma, and injury severity score (ISS) ≥27, age ≥18 years old, and had length of hospital stay >15 days. Exclusion criteria included previous medical history of malignancy, or immunological, consumptive, and metabolic diseases. The patient’s clinical characteristics, ISS scores, Glasgow coma scale (GCS), sequential organ failure assessment, APACHEⅡ scores, and nutrition and immune indexes on day 3 after injury were collected. The difference between the PICS group and N-PICS group were performed by Student’s t test, χ2 test or Mann-Whitney U test. The early risk factors were assessed in patients with PICS after severe polytrauma by logistic regression analysis. Results:According to the diagnostic criteria of PICS, all enrolled patients were divided into two groups: PICS group ( n=102) and N-PICS group (without PICS, n=174). Compared with the N-PICS group, patients in the PICS group were older and associated with more brain and chest injuries. On the third day after injury, serum levels of IL-6 and IL-10, and the ratio of Treg cells were significantly higher, the number and ratio of NK cells subset, and the ratio of activated T lymphocyte were significantly lower in the PICS group than in the N-PICS group ( P<0.05). Logistic regression analysis showed that the age>65 years old ( OR=2.375, 95% CI: 1.442-4.531), GCS ≤8 scores ( OR=3.431, 95% CI: 1.843-8.512), IL-10 >10 pg/mL ( OR=2.173, 95% CI: 1.751-5.614), the ratio of Treg cells >7% ( OR=3.871, 95% CI: 1.723-6.312), and the occurrence of traumatic brain and chest injuries ( OR=2.846, 95% CI: 1.522-5.361) were the early risk factors in patients with PICS after severe polytrauma. Conclusions:Age>65 years old, GCS score, IL-10, the ratio of Treg cells, and the occurrence of traumatic brain and chest injuries could be used as the early risk factors in patients with PICS after severe polytrauma. The discovery of early risk factors will help identify patients at high risk of PICS after severe polytrauma, and create the possibility for early intervention.

Consideration on defining polytrauma as a single disease / 中华创伤杂志

Polytrauma represents severe injuries to multiple body regions, which is associated with high risk of complications and mortality. The definition of polytrauma relies on the basic concept of a combination of injuries that cause a life-threatening condition. The authors strongly call on the healthcare community to list polytrauma as a single disease in the international classification of diseases, rather than "disease combination". Because polytrauma has definite etiology and unique pathophysiological changes after polytrauma, treatment models are different from single trauma. Polytrauma can certainly fulfil any practical and nosological criteria of a single disease according to Berlin definition. The authors explore the importance of polytrauma as a single disease in preventive intervention strategies, therapeutic measures and traumatology development in the future.

Traumatic recurrent hip dislocation associated with femoral head fracturere constructed with iliac crest autograft / Luxación recurrente de cadera asociada a fractura de cabeza femoral reconstruida con autoinjerto de cresta iliaca

Hip femoral head fractures are extremely uncommon, but likely associated with traumatic hip dislocations. Both lesions require emergent treatment to avoid further complications.19-year-old male patient was received after a high-energy motor vehicle accident with severe brain and thoraco-abdominal trauma and a displaced femoral head fracture with posterior hip dislocation with no acetabular fracture. An emergent open reduction and internal fixation with 2 headless screws was performed, as well as posterior capsule repair. After 1 month as an inpatient in Intensive Care Unit, he sustained a new episode of posterior hip dislocation. Consequently, a second successful surgical reduction was obtained, and hip stability was achieved by posterior reconstruction with iliac crest autograft fixed with cannulated screw and posterior structure repair. Two years later, he was able to walk independently and he does not present any signs of degenerative joint disease nor avascular necrosis.

Las fracturas de la cabeza femoral son extremadamente raras y están asociadas comúnmente con una luxación de cadera traumática. Ambas lesiones requieren tratamiento urgente con el objetivo de evitar complicaciones posteriores. Un paciente varón de 19 años fue trasladado tras un accidente de tráfico de alta energía en el que sufrió un traumatismo craneoencefálico y toracoabdominal grave, además de una fractura de cabeza femoral desplazada junto a una luxación posterior de cadera sin afectación acetabular. De manera urgente, fue intervenido mediante una reducción abierta y fijación interna de la fractura con dos tornillos canulados sin cabeza y reparación de la cápsula articular posterior. Tras un mes de ingreso en la unidad de cuidados intensivos, sufrió un nuevo episodio de luxación posterior de cadera. Debido a ello, se realiza una segunda intervención quirúrgica con reducción abierta y en la que se obtiene una adecuada estabilidad de la cadera mediante reconstrucción posterior con la adición de autoinjerto tricortical de cresta ilíaca y reparación capsular posterior. Después de dos años de seguimiento, el paciente deambula de manera independiente, sin dolor y sin signos degenerativos ni de necrosis avascular en las pruebas de imagen.

Damage control in orthopaedical and traumatology

In Orthopedics, damage control is indicated in patients with pelvic and/or long bone fractures associated with hemodynamic instability. It is inappropriate to perform a complex definitive reduction and fixation surgery for severely injured trauma patients with hemodynamic instability. In these cases, it is recommended to perform minimally invasive procedures that temporarily stabilize the fractures and bleeding control. Closed or open fractures of the long bones such as femur, tibia, humerus, and pelvis can lead to hemodynamic instability and shock. Thus, orthopedic damage control becomes a priority. However, if the patient is hemodynamically stable, it is recommended to stabilize all fractures with an early permanent internal fixation. These patients will have a shorter hospital length of stay and a reduction in mechanical ventilation, blood components transfusions and complications. Therefore, the concept of orthopedic damage control should be individualized according to the hemodynamic status and the severity of the injuries. Open fractures, dislocations, and vascular injuries could lead to permanent sequelae and complications if a correct management and approach are not performed.

En Ortopedia se indica control del daño en pacientes que presentan fracturas de pelvis y/o huesos largos asociado a condiciones generales inestables. Dada la severidad del trauma asociada a inestabilidad hemodinámica no es adecuado realizar una cirugía definitiva compleja de reducción y fijación de todas sus fracturas. En estos casos se recomienda realizar procedimientos poco invasivos que permitan estabilizar provisionalmente las fracturas, para; disminuir el dolor, controlar la hemorragia de las fracturas, obtener una alineación adecuada de los huesos fracturados y reducir las luxaciones. Estas medidas permiten controlar el daño del primer golpe para así disminuir las complicaciones. Las fracturas de los huesos largos fémur, tibia, húmero y pelvis cerradas o abiertas pueden llevar a una inestabilidad y estado de shock. Mientras que el paciente no tenga alteración hemodinámica, se recomienda estabilizar todas sus fracturas precozmente con una fijación interna que controle esta forma el daño y la necesidad de tiempo de hospitalización. Como resultado se disminuyen los días en cuidados intensivos, la ventilación mecánica, las transfusiones y las complicaciones. El concepto de control de daño para el manejo de las lesiones ortopédicas se debe individualizar de acuerdo a las condiciones generales de cada paciente y la gravedad de sus lesiones como: fracturas abiertas, luxaciones, luxación completa de la articulación sacroíliaca, luxofractura del talo, y lesiones vasculares, ya que estas lesiones requieren un manejo prioritario inicial generalmente definitivo en la mayoría de los pacientes con politraumatismo para evitar complicaciones serias futuras que pueden dejar secuelas definitivas al no recibir el tratamiento adecuado inicial.

Hipotensión permisiva en trauma / Permissive hypotension in trauma

Resumen Introducción: El shock hemorrágico es una de las causas más comunes de muerte en pacientes con trauma debido a que pone en marcha un círculo vicioso de mecanismos que incluyen hipotermia, acidosis y coagulopatía. Para mitigar estos efectos, se han propuesto estrategias de control de daños, incluido el aporte controlado de líquidos con hipotensión permisiva contemplando metas en la presión arterial sistólica para mantener una adecuada perfusión de los tejidos. Objetivo: Conocer información actualizada acerca del manejo de la hipotensión permisiva en pacientes con trauma. Metodología: Se buscó información en las bases de datos Web-of-Science y Scopus de los últimos cinco años. El resultado arrojó un total de 118 artículos de los cuales se tomaron 30, según los criterios de inclusión y exclusión. Resultados: Todos los artículos consideran el uso de la hipotensión permisiva como una buena opción para el manejo de los pacientes con trauma e hipotensión, sin embargo, difieren en qué momento es adecuado utilizarlo y en qué condiciones se debe realizar. Conclusiones: Si bien la hipotensión permisiva se ha convertido en uno de los pilares fundamentales en el manejo prehospitalario del paciente con trauma, se requieren estudios investigativos en humanos para soportar cuándo y cómo debe utilizarse.

Abstract Introduction: Hemorrhagic shock is one of the most common causes of death in trauma patients, because it sets in motion a vicious cycle of mechanisms, including hypothermia, acidosis, and coagulopathy. To mitigate these effects, damage control strategies have been proposed, including the controlled intake of fluids with permissive hypotension, contemplating goals in systolic blood pressure, and thus, maintaining adequate tissue perfusion. Objective: The present research aimed to review the literature in search of updated information about the management of permissive hypotension in patients with trauma. Methodology: Information was searched in the Web-of-Science and Scopus databases in the last five years. The result yielded a total of 118 articles, of which 30 were taken according to the inclusion and exclusion criteria. Results: All the articles consider the use of permissive hypotension as a good option for the management of patients with trauma and hypotension, however, they differ when it is appropriate to use it and under what conditions it should be performed. Conclusions: Although permissive hypotension has become one of the fundamental pillars in the prehospital management of the patient with trauma, research studies in humans are required to support when and how it should be used.

A prospective study of clinical characteristics and prognosis in patients with persistent inflammation, immunosuppression and catabolism syndrome after polytrauma / 中华急诊医学杂志

Objective:To prospectively assess clinical characteristics, potential causes and prognosis in patients with persistent inflammation, immunosuppression and catabolism syndrome (PICS) after polytrauma.Methods:Totally 1 083 patients with polytrauma admitted to Department of Traumatic Surgery of Tongji Hospital from Janury 2019 to July 2020 were enrolled. Exclusion criteria included age<18 years old, length of hospital stay<15 days, previous medical history of malignancy, or immunological, consumptive, and metabolic diseases. According to the diagnostic criteria of PICS, all enrolled patients were divided into two groups: PICS group and N-PICS group (without PICS). The patient’s clinical characteristics, ISS score, GCS score, SOFA score, and prognosis were collected. The χ2 test or Student’s t test was uesd to compare the difference between the PICS group and N-PICS group. Results:The incidence of PICS in patients with polytrauma was 11.7% (127/1 083). The majority of PICS patients were middle-aged and elderly men, 68.5% with traumatic brain injury and 59% with thoracic injury. GCS score was significantly lower, while ISS, APACHE II and SOFA scores were significantly higher in the PICS group than in the N-PICS group ( P<0.01, P<0.05). Among PICS patients, 79.5% were treated with mechanical ventilation and 76.3% were associated with pulmonary infection, with a 28-day mortality of 5.5% and a 180-day mortality of 16.5%, which were siginifcantly different from those without PICS. Conclusions:PICS has a high incidence after polytrauma and is commonly seen in middle-aged and elderly male patients with severe polytrauma, especially accompanied by traumatic brain injury or/and thoracic injury. Patients with PICS after polytrauma have poor long-term prognosis, so early identification and intervention should be strengthened in clinical practice.

Pattern of injuries due to wild animal attack among patients presenting to the emergency department: A retrospective observational study / 中华创伤杂志(英文版)

PURPOSE@#The human-wildlife conflicts (HWCs) causing nuisances and injuries are becoming a growing public health concern over recent years worldwide. We aimed to study the demographic profile, mode of injury, pattern of injury, and outcome of wild animal attack victims presented to the emergency department.@*METHODS@#This retrospective cross-sectional study was conducted in the emergency department of a tertiary-care hospital in Eastern India. Data were retrieved from the medical records from May 2017 to May 2021. Patients of all ages and genders attacked by wild animals and secondary injuries were included in this study. Patients with incomplete data, injuries due to the attack of stray and domestic animals and trauma due to other causes were excluded. Demographic profile, mode of injury, the pattern of injury, injury severity score (ISS), radiological pattern, and outcome were recorded. Statistical analysis with R (version 3.6.1.) was conducted.@*RESULTS@#A total of 411 wild animal attack victims were studied, of which 374 (90.9%) were snakebite injuries and 37 (9.1%) were wild mammalian (WM) attack injuries. The mean age of WM attack victims was 46 years, and the male-to-female ratio was 4:1. Elephant attack injury (40.5%) was the most common WM attack injury reported. Most WM attacks (43.2%) occurred between 4:00 a.m. to 8:00 a.m. The median ISS was 18.5 (13-28), where 54.2% of patients had polytrauma (ISS>15). Elephant attack was associated with a higher ISS, but the difference was not significant compared to other animal types (p = 0.2). Blunt trauma was common pattern of injury in the elephant attack injury cases. Lacerations and soft tissue injuries were common patterns in other animal attacks. Among snakebites, neurotoxic was the most common type (55.4%), and lower extremity was the most common site involved.@*CONCLUSION@#The young male population is the major victim of HWCs; and elephant is the most common animal involved. There is a need to design scientifically sound preventive strategies for HWCs and to strengthen the preparedness in health establishments to manage victims effectively.

Spinal Cord Injuries ­ When Is the Initial Tomography Insufficient?

Introduction Spinal cord injury (SCI) is common in polytrauma patients. The standard exam for the initial evaluation is computed tomography (CT), due to its higher sensitivity and specificity when compared with plain radiographs. However, CT is insufficient for themanagement of some cases, especially to evaluate ligamentous and spinal cord injuries. The objective of the present study is to describe clinical scenarios in which the CT scan was insufficient to guide the treatment of SCIs. Methods We present the cases of four polytrauma patients with normal CT scans at admission and with unstable or surgically-treated lesions. Discussion The cases reported evidence the need for ongoing neurological surveillance with serial physical examination and magnetic resonance imaging (MRI) in cases of neurological injury not explained by CT or occult instability. Conclusion Computed tomography is not always sufficient to determine the management of SCIs. A comprehensive evaluation of the clinical data, CT findings and, occasionally, MRI findings is crucial in order to choose the best conduct.

Sistemática en el Tratamiento Quirúrgico de las Fracturas Panfaciales Aplicado a un Caso Clínico De Alta Complejidad / Systematic in the Surgical Treatment of Panfacial Fractures Applied to a Highly Complex Clinical Case

RESUMEN: Las fracturas panfaciales son aquellas que afectan de forma simultánea al tejido óseo de dos o más tercios del rostro. El manejo inicial de estos pacientes es resolver o estabilizar las urgencias médico - quirúrgicas que puedan presentar, debido a que la gran mayoría de estas fracturas están asociadas a traumatismos de alta energía cinética, las que determinan la presencia de lesiones concomitantes que pueden comprometer la vida del paciente. El tratamiento quirúrgico de las fracturas panfaciales puede abarcar desde la intervención quirúrgica inicial de control de daños, estabilización, reducción y fijación quirúrgica de los segmentos fracturados mediante osteosíntesis hasta intervenciones mediatas para la reconstrucción de los tejidos afectados por el traumatismo. Para el tratamiento de las fracturas panfaciales existe una sistemática quirúrgica que tiene por objeto contener y/o minimizar daños agudos y permitir una reducción morfológica y funcional. Reportamos un caso clínico de fractura panfacial cuyo tratamiento siguió esta sistemática terapeútica.

ABSTRACT: Panfacial fractures affect bone tissue in two or more thirds of the face simultaneously. The initial management of these patients is to resolve or stabilize the medical-surgical emergencies that they may present. Most of these fractures are associated to trauma of high kinetic energy, which determine the presence of concomitant inju- ries that can compromise the life of the patient. The surgical treatment of panfacial fractures may include from the initial surgical intervention of damage control, stabilization, reduction and surgical fixation of fractured segments through osteosynthesis, to mediate the reconstruction of tissues affected by the trauma. For the treatment of panfacial fractures there is a surgical approach that aims to contain and/or minimize acute damage and allow for morphological and functional reduction. We report a clinical case of panfacial fracture whose treatment followed this therapeutic approach.

Hemoterapia en el paciente gravemente enfermo / Hemotherapy in the seriously ill patients

Introducción: Para mejorar la estabilidad hemodinámica, trastornos de la coagulación, perfusión hística, capacidad de transporte de oxígeno, entre otros, en el paciente crítico se hace necesario la transfusión de sangre y derivados. Objetivo: Caracterizar la población de pacientes graves que recibieron tratamiento con sangre y hemoderivados. Métodos: Se realizó un estudio descriptivo y transversal en 199 pacientes ingresados en la unidad de cuidados intensivos del Hospital General Orlando Pantoja Tamayo del municipio Contramaestre, provincia Santiago de Cuba, desde enero de 2016 hasta abril de 2019. Las variables analizadas fueron: edad, sexo, causas de hemoterapia, tipo de componente sanguíneo empleado, frecuencia de administración, reacciones adversas y estado al egreso. Se utilizó el porcentaje para resumir la información, así como el test chi cuadrado para identificar asociación estadística. Resultados: Predominaron el sexo femenino (56,7 por ciento) y la edad comprendida entre 65 años y más, con el diagnóstico de politraumatizados, sangrado digestivo alto y sepsis. El concentrado de hematíes fue el más empleado y la frecuencia de administración, en una ocasión, fue en la categoría que más reacciones adversas se encontró (56,6 por ciento); el empleo en cuatro o más ocasiones incrementó la mortalidad. Conclusiones: El concentrado de hematíes fue el hemoderivado más administrado, la administración en una ocasión fue la que más reacciones adversas provocó y la mayoría fueron del tipo inmediatas inmunológicas(AU)

Introduction: To improve hemodynamic stability, coagulation disorders, tissue perfusion, oxygen transport capacity, among others, the transfusion of blood and plasma derivatives is necessary in the critically-ill patient. Objective: To characterize the population of seriously-ill patients who received treatment with blood and hemoderivatives. Methods: A descriptive and cross-sectional study was carried out with 199 patients admitted to the intensive care unit of Orlando Pantoja Tamayo General Hospital in Contramaestre Municipality, Santiago de Cuba Province, from January 2016 to April 2019. The variables analyzed were age, sex, causes for hemotherapy, type of blood component used, frequency of administration, adverse reactions, and discharge status. Percentage was used to summarize the information. Also, the chi-square test was used to identify statistical association. Results: There was a predominance of the female sex (56.7%) and of the age 65 years and older, with diagnosis of polytrauma, high digestive bleeding, and sepsis. The red blood cell concentrate was the most used and the frequency of administration, on one occasion, occurred in the category with the highest amount of adverse reactions (56.6%). Administration on four or more occasions increased mortality. Conclusions: The red blood cell concentrate was the most administered hemoderivative. Administration on one occasion that caused the most adverse reactions and most were immediate immunological ones(AU)

Factor tiempo en la atención inicial del paciente politraumatizado / Factor time in the initial attention of the poly-traumatized patient

RESUMEN Introducción: el politraumatismo por si solo constituye uno de los problemas más grandes de la sociedad moderna. Las lesiones traumáticas en Cuba aparecen en el quinto lugar entre las causas globales de muerte para todas las edades. Objetivo: determinar cómo incidió el factor tiempo en la organización de las acciones para la atención de urgencia al paciente politraumatizado. Materiales y método: se realizó un estudio observacional, conformado por 183 pacientes politraumatizados, atendidos en la Unidad de Cuidados Intensivos Emergentes del Hospital Provincial". José R. López Tabrane " de Matanzas, durante el año 2014. Las variables a considerar fueron: edad, sexo, tiempo en que recibieron las primeras acciones, tiempo de llegada al Hospital, factores asociados que influyeron en la aparición de injuria secundaria. Se utilizó la técnica estadística de análisis de distribución de frecuencias. Resultados: el mayor porcentaje de los pacientes (82,6 %) acudieron 4-6 h después de sufrido el traumatismo. Aparecieron factores como la hipotensión, la hipoxia (66,1 y 50,2 %) respectivamente, que tuvieron lesiones asociadas y fueron valoradas en la primera hora del traumatismo. Conclusiones: el trauma severo es una de las entidades prevenibles que más vida cobra en la sociedad. El sexo masculino y edades más productivas de la vida fueron los que más morbimortalidad presentaron. El hecho de que la mayor cantidad de estos pacientes arribaron al Hospital después de la hora dorada, propició un mayor número de complicaciones por el no control a tiempo de los elementos que forman la injuria secundaria (AU).

ABSTRACT Introduction: polytrauma, by itself, is one of the biggest problems of the modern society. Trauma lesions in Cuba are in the fifth place among the death global causes for all age groups. Objective: to determine how time factor had an impact in the actions organization for the emergency care to polytrauma patient. Materials and method: an observational study was performed in 183 poly-trauma patients who attended the Intensive Care Unit of the Provincial Hospital "Jose Ramón López Tabrane" of Matanzas during 2014. The considered variables were: age; sex; time of receiving the first actions; time of arrival to the hospital; associated factors influencing in the appearance of secondary injury. The authors used the statistic technique of analysis of frequency distribution. Results: the highest percent of patients (82.6 %) assisted the consultation 4-6 hours after suffering the trauma. There were found factors like hypotension and hypoxia (66.1 and 50.2 % respectively that had associated lesions and were assessed in the first hour of the trauma. Conclusions: acute trauma is one of the preventable entities taking more lives in the society. Male sex predominated and the more productive ages of life were the ones presenting more morbid-mortality. The fact that the biggest quantity of these patients arrived to the hospital after the golden hour favored a higher number of complications due to the untimely control of the elements forming the secondary injury (AU).

Major trauma and severe burn: a synergistic mortality: case report and literature review / Traumatismo grave y quemadura severa: una mortalidad sinérgica: reporte de un caso y revisión bibliográfica

CASE PRESENTATION: A 42-year-old man was transferred to our institution after a highenergy accident (an explosion). He presented second-degree burns on 20% of the total body surface area (TBSA), affecting the lower hemiabdomen and the lower right limb. He also presented a supraintercondylar open fracture of the right femur (Gustilo I). The burns were treated with debridement and coverage withmesh graft, while the fracture required an early transitory transarticular external fixation with delayed definitive osteosynthesis. Our patient presented good local and systemic evolution. We can offer a eleven-month follow-up. DISCUSSION: The literature supports that the combination of trauma and burn injuries is a relatively rare pattern, which may explain the lack of knowledge and studies on this subject. This double injury has demonstrated a synergistic effect on mortality. The management of soft tissues in the coexistence of an open fracture and a burn in the same limb is a challenge. The method and timing of the treatment of the fracture directly impacts the treatment of the burn (and vice versa), and most authors tend to treat the fracture first. All of the studies reviewed emphasized the importance of the multidisciplinary approach. CONCLUSIONS: We have presented a complex case combining major trauma and severe burns. Although there is a lack of studies in the literature on this subject, the papers state that this is an unusual pattern with a synergistic effect on mortality. In our experience, the management of soft tissues and the multidisciplinary approach play a central role, as it is also stated in the literature. The management of these patients is still controversial, and more studies are needed.

PRESENTACIÓN DEL CASO: Hombre de 42 años trasladado a nuestra institución tras un accidente de alta energía (explosión). Presentaba quemaduras de segundo grado del 20% de la superficie corporal total (SCT), afectando el hemiabdomen inferior y la extremidad inferior derecha. También presentaba una fractura abierta supraintercondílea de fémur derecho (Gustilo I). Las quemaduras fueron tratadas mediante desbridamiento y cobertura mediante injerto mallado, mientras que la fractura requirió un fijador externo transarticular precoz de forma transitoria con una osteosíntesis definitiva diferida. Nuestro paciente presentó buena evolución local y sistémica. Podemos ofrecer un seguimiento a 11 meses. DISCUSIÓN: La bibliografía defiende que la lesión combinada de traumatismo y quemadura es un patrón relativamente raro, pudiendo explicar la falta de conocimiento y publicaciones al respecto. Este doble insulto ha demostrado un efecto sinérgico en la mortalidad. El manejo de las partes blandas cuando coexisten una fractura abierta y una quemadura en la misma extremidad es un desafío. El método y el momento de tratamiento de la fractura impactan de forma directa en el tratamiento de la quemadura (y viceversa); y la mayoría de los autores tienden a tratar en primer lugar la fractura. Todos los estudios analizados enfatizan la importancia del abordaje multidisciplinario. CONCLUSIONES: Hemos presentado un caso complejo combinando traumatismo grave y quemaduras severas. Aunque haya una falta de bibliografía, los estudios afirman que se trata de un patrón inusual con un efecto sinérgico sobre la mortalidad. En nuestra experiencia, el manejo de las partes blandas y el abordaje multidisciplinario tienen un rol central, tal y como defienden también los artículos publicados. El manejo de estos pacientes sigue siendo controvertido, y son necesarios más estudios.

Trichosporon asahii fungaemia in an immunocompetent polytrauma patient who received multiple antibiotics

@#Trichosporon asahii is a yeast-like fungus that is emerging as an important cause of invasive infections in tertiary medical centres. A 58-year-old Chinese man with no known medical illnesses presented with liver lacerations and multiple fractures following an alleged 12-foot fall at a construction site. The gravity of his injuries and poor haemodynamic status necessitated an intensive care unit (ICU) admission, during which several febrile episodes were detected and multiple antibiotics were administered. After being in the ICU for at least two weeks, a urease-positive yeast was isolated from the patient’s blood. The yeast formed dry, fuzzy and wrinkled white colonies on Sabouraud dextrose agar following prolonged incubation, and produced blastoconidia, true hyphae, pseudohyphae and arthroconidia on slide culture. It was identified biochemically by the ID 32 C kit as T. asahii. The yeast had elevated minimal inhibitory concentration (MIC) values to fluconazole, amphotericin B, flucytosine and all echinocandins tested. In view of this, the patient was treated with voriconazole and was successfully transferred to the general medical ward.

Factores de riesgo de mortalidad en pacientes politraumatizados / Risk factor for mortality in polytraumatized patients

Introducción: El trauma es considerado un problema de salud pública a nivel mundial. También es causa importante de morbilidad y mortalidad en el mundo. Objetivo: Identificar factores de riesgo y causas de mortalidad en pacientes politraumatizados. Métodos: Se realizó un estudio descriptivo, longitudinal y retrospectivo en pacientes politraumatizados mayores de 18 años intervenidos quirúrgicamente en la unidad de urgencias del Hospital Universitario General Calixto García durante un año de observación. Se describieron variables sociodemográficas, se estimaron los tiempos de atención médica inicial y se describió la condición clínica del paciente al llegar al quirófano. Igualmente se relacionó la aparición de muerte con el trauma predominante y otros factores perioperatorios. Se utilizaron procederes estadísticos univariados para factores de riesgo y análisis multivariado para predecir factores pronósticos de mortalidad. Resultados: Hubo una asociación significativa entre mortalidad y presencia de diabetes mellitus e hipertensión arterial como enfermedades asociadas; entre el trauma múltiple con trauma craneoencefálico, la presencia de shock hipovolémico, uso de aminas y Glasgow por debajo de ocho al llegar al quirófano, así como la respuesta inflamatoria sistémica, hipertensión endocraneal e insuficiencia respiratoria aguda como complicaciones perioperatorias. Como factores pronósticos de muerte se identificaron el shock hipovolémico, la respuesta inflamatoria sistémica y el menor Glasgow. Conclusiones: Se identificaron nueve factores de riesgo con significación estadística y tres factores pronósticos de riesgo independiente para mortalidad en pacientes politraumatizados(AU)

Introduction: Trauma is considered a public health problem worldwide. It is also an important cause of morbidity and mortality in the world. Objective: To identify risk factors and causes of death in polytraumatized patients. Methods: A descriptive, longitudinal and retrospective study was carried out in polytraumatized patients aged more than 18 years and surgically treated in the emergency unit of General Calixto García University Hospital during one year of observation. Sociodemographic variables were described, initial medical attention times were estimated, and the patient's clinical condition was described upon arrival at the operating room. The occurrence of death was considered based on its association with the predominant trauma and other perioperative factors. Univariate statistical procedures were used for risk factors. Multivariate analysis was used to predict prognostic factors for mortality. Results: There was a significant association between mortality and presence of diabetes mellitus and hypertension as associated diseases; as well as between multiple trauma with cranioencephalic trauma, the presence of hypovolemic shock, use of amines and Glasgow score below eight on arrival at the operating room, as well as the systemic inflammatory response, intracranial hypertension and acute respiratory failure as perioperative complications. Prognostic factors for death were hypovolemic shock, the systemic inflammatory response and lower Glasgow score. Conclusions: We identified nine risk factors with statistical significance and three prognostic factors of independent risk for mortality in polytraumatized patients(AU)

Evaluación de protocolos para la atención inicial del trauma maxilofacial grave / Evaluation of protocols for the initial management of severe maxillofacial trauma

Introducción: el trauma maxilofacial es uno de los mayores retos para los servicios públicos de salud por su alta incidencia. Los protocolos mejoran la calidad de la atención y reducen la variación de la práctica clínica, por lo que es vital contar con una protocolización de alta calidad en esta área. Objetivo: evaluar protocolos de atención en la urgencia de pacientes politraumatizados, politraumatizados maxilofaciales y trauma maxilofacial grave. Métodos: se realizó un estudio descriptivo, transversal con enfoques cualitativos de mayo a junio de 2015. Se efectuó una búsqueda en Internet de protocolos de atención de urgencia del politraumatizado, politraumatizado maxilofacial y trauma maxilofacial grave en español, inglés o portugués; y nacionalmente por correo electrónico y teléfono. Se creó un instrumento evaluativo y un grupo evaluador. Se trabajó con números enteros, índices y medias. Resultados: el Protocolo de tratamiento inicial del paciente politraumático obtuvo 275 puntos, seguido por el Soporte Vital Avanzado de Trauma con 229 (índice de dificultad total de 0,93 y 0,70, respectivamente). El protocolo extranjero maxilofacial obtuvo 150 (índice de dificultad total 0,46). El ítem dos alcanzó 128 puntos (índice de dificultad total 1). El protocolo del Hospital Calixto García obtuvo 223 (índice de dificultad total 0,73) y los de Matanzas y Villa Clara 120 cada uno (índice de dificultad total 0,32). El ítem de mayor puntuación fue el cuatro con 74 puntos (índice de dificultad total 0,54). Conclusiones: los protocolos extranjeros de mayor calidad fueron Tratamiento inicial del paciente politraumático y Soporte Vital Avanzado de Trauma y el ítem mejor elaborado fue el dos. Los mejores protocolos nacionales fueron Atención al trauma grave del Hospital Calixto García y el de las provincias Villa Clara y Matanzas, y el ítem de mejor elaboración fue el cuatro(AU)

Introduction: due to its high incidence, maxillofacial trauma is one of the greatest challenges for public health services. Protocols improve the quality of care and reduce variation in clinical practice, hence the crucial importance of high-quality protocolization in the area of trauma care. Objective: evaluate the care protocols followed in the emergency management of polytrauma, maxillofacial polytrauma and severe maxillofacial trauma. Methods: a descriptive cross-sectional qualitative study was conducted from May to June 2015. An online search was carried out for protocols for the emergency management of polytrauma, maxillofacial polytrauma and severe maxillofacial trauma in Spanish, English and Portuguese. A parallel national search was performed by telephone and electronic mail. An evaluation tool was developed and an evaluation team was formed. Estimations were based on integers, indices and means. Results: the Protocol for Initial Management of Polytrauma scored 275 points, followed by Advanced Trauma Life Support with 229 (total difficulty index 0.93 and 0.70, respectively). The foreign maxillofacial protocol scored 150 points (total difficulty index 0.46). Item 2 scored 128 points (total difficulty index 1). The protocol from Calixto García Hospital scored 223 points (total difficulty index 0.73), and the ones from Matanzas and Villa Clara scored 120 each (total difficulty index 0.32). Item 4 had the highest score, with 74 points (total difficulty index 0.54). Conclusions: the highest quality foreign protocols were Initial Management of Polytrauma and Advanced Trauma Life Support, and the best developed item was number 2. The best national protocols were Management of Severe Trauma, from Calixto García Hospital, and the ones from the provinces of Villa Clara and Matanzas. The best developed item was number 4(AU)

Ruptura diafragmatica postraumatica en pediatria: A proposito de un caso / Post traumatic diaphragmatic rupture in children: Case report

La ruptura diafragmática es una entidad relativamente infrecuente en pediatría que se puede presentar como consecuencia de un traumatismo de alto impacto. Solo entre el 25% y el 50% de los casos es detectado en la evaluación inicial del paciente, lo que aumenta el riesgo de complicaciones. En este trabajo, se presenta el caso de una paciente asintomática, de 8 años de edad, que, tras un accidente vehicular y la evaluación inicial en otro centro, fue derivada a nuestra Institución para el control evolutivo. A las 36 horas del ingreso, presentó hipoventilación pulmonar izquierda. La tomografía demostró un ascenso intratorácico del ángulo esplénico del colon y asas de intestino delgado. Se efectuó la exploración y el tratamiento quirúrgico. Los controles radiográficos diferidos no mostraron signos de recidiva.

Diaphragmatic rupture is a relatively uncommon entity in pediatrics that can occur as a result of a high-impact trauma. Only between 25 and 50% of the cases are detected in the initial evaluation of the patient, which increases the risk of complications. This paper presents the case of an asymptomatic 8-year-old patient who was referred to our institution after a vehicular accident. A day and a half after admission, a left pulmonary hypoventilation was detected. Computed tomography scan showed intrathoracic elevation of the splenic angle of the colon and the small bowel. Surgical exploration and treatment were performed. Deferred radiographic controls showed no signs of relapse.